Interactions of tuftsin with bovine serum albumin.
نویسندگان
چکیده
Interactions of tuftsin (Thr-Lys-Pro-Arg) with bovine serum albumin (BSA) were analysed by fluorescence spectroscopy and circular dichroism. The data show that tuftsin interacts weakly with BSA, but this interaction is considerably enhanced by introducing an apolar substituent at the C-terminus of the tetrapeptide. It is suggested that strong binding of tuftsin to albumin in blood may enhance its macrophage-stimulating activity in vivo.
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عنوان ژورنال:
- FEBS letters
دوره 205 2 شماره
صفحات -
تاریخ انتشار 1986